• 南宫NG·28(中国)相信品牌力量有限公司

    Apeloa
    南宫28药业
    DS Technology Platforms
    Flow Chemistry Synthetic Biology & Biocatalysis Highly Potent Compound Peptide TPD/PROTAC Oligonucleotide Synthesis Crystallization & Particle Engineering Preparation & Separation
    Flow Chemistry Platform
    Apeloa has established an industry-leading flow chemistry platform with over a decade of flow chemistry experience, a multi-site network of manufacturing, development, and analytical facilities, combined with world-class scientists. Our state-of-the-art facilities offer quick and economical viable solutions to tackle process challenges under conventional batch mode, with services from feasibility, process development and optimization (PD&O), scale-up to commercial production.
    南宫28药业
    Team
    Our flow chemistry services are supported by highly educated and experienced teams across our global network facilities. Our Boston (USA) site offers leading expertise in early-stage flow chemistry, while our Shanghai and Hengdian (China) sites can efficiently develop gram to kilogram scale samples, supported by advanced analytical technology and skilled scientists.
    Service
    南宫28药业
    Apeloa offers comprehensive flow chemistry expertise covering the entire lifecycle, from early development to manufacturing of intermediates and active pharmaceutical ingredients (APIs).
    Feasibility study (FTE/FFS for early stage development)
    Process development & optimization (PD&O)
    Scale-up and Proof of concept study
    Commercial equipment design
    Variable scale sample preparation
    Non-GMP and cGMP commercial manufacturing
    The advantages of fluid chemistry: green, safe, economical, fast, and flexible
    Flow Chemistry Reactions
    南宫28药业
    Flow chemistry can be an ideal approach for synthesis routes involving high-risk conditions, such as highly exothermic, explosive, light-activated, or highly complex multi-step synthesis routes. Apeloa has demonstrated scientific excellence with a wide range of flow chemistry reactions.
    Range of Flow Chemistry Reactors
    Apeloa has built a full complement of flow chemistry reactors for different scale and stage of development, including lab-scale reactors (g to 1kg scale) and Non-GMP & cGMP commercial production scale reactors (up to tons/year).
    Laboratory scale fluid reactor :
    Microreactors (stainless steel, silicon carbide, Hastelloy&glass)
    Tubular reactors (stainless steel and Hastelloy)
    Tangential reactor (stainless steel and Hastelloy)
    Photoreactor (light) with adjustable UVLED radiation and glass tube
    Circulating reactor
    Non GMP/GMP commercial scale fluid reactors :
    Microreactor
    Tubular reactor (Monel alloy)
    Tubular reactor (stainless steel 316L)
    • MICRO REACTOR
      MICRO REACTOR
    • TUBULAR REACTOR
      TUBULAR REACTOR
    • CSTR
      CSTR
    • TANGENTIAL REACTOR(HC)
      TANGENTIAL REACTOR(HC)
    • PHOTO REACTOR
      PHOTO REACTOR
    • MICRO REACTOR-Glass
      MICRO REACTOR-Glass
    南宫28药业
    MICRO REACTOR
    南宫28药业
    TUBULAR REACTOR
    南宫28药业
    CSTR
    南宫28药业
    TANGENTIAL REACTOR(HC)
    南宫28药业
    PHOTO REACTOR
    南宫28药业
    MICRO REACTOR-Glass